Table 2.

Longitudinal change in neuropsychological test performance in APOE ϵ4 homozygotes, heterozygotes, and all carriers relative to noncarriers (linear and quadratic effects)

Abbreviations: AVLT-LTM = Auditory Verbal Learning Test–Long-Term Memory; Cat = categories completed; COWAT = Controlled Oral Word Association Test; DiSp = Digit Span; DSS = Digit Symbol Substitution; HMZ = homozygote; HTZ = heterozygote; NC = noncarrier; PAI-Man-A = Personality Assessment Inventory Mania Activity Subscale; PASAT = Paced Auditory Serial Attention Task, 3-second (PASAT-3) and 2-second (PASAT-2) versions; Perr = perseverative errors; Terr = total errors; WAIS = Wechsler Adult Intelligence Scale–Revised; WCST = Wisconsin Card Sorting Test.

^aSignificant.