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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Immunol. 2010 Oct 27;185(11):6448–6460. doi: 10.4049/jimmunol.1000889

Table I.

Cytokine secretion from SMX and SMX metabolite stimulated T-cell clones from hypersensitive patients.

Cytokine (pg/ml)a
id CD IL4 IL5 IL6 IL8 IL13 IL17 IFNγ TNFα GMCSF
SMX-stimulated clones
1 8 -b - - - 426 32 544 358 271
2 4 137c 28190 - 25 16157 62 33 149 273
3 8 136 373 13 59 18204 71 1202 1967 991
4 4 - - 56 1408 7375 57 8004 3346 1676
5 8 - 14 - - 726 36 108 34 108
SMX-metabolite-stimulated clones
1 8 55 1791 323 56 >20000 77 817 2058 827
2 4 - - - - 1012 37 441 953 441
3 4 - - 11 56 978 35 326 855 326
4 4 16 12 186 295 7742 56 947 2499 947
a

No detectable drug-specific secretion of IL-1β, IL-7, IL-10 & MCP-1.

b

-; not detectable.

c

Data represents mean of duplicate cultures with cytokine levels (less than 10pg/ml IL4, IL5, IL6, IL-8, TNFα; less than 20pg/ml IFNγ; less than 50pg/ml IL13, IL17, GMCSF) in drug-free wells subtracted.