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. Author manuscript; available in PMC: 2011 May 4.
Published in final edited form as: Transl Res. 2009 Jan 21;153(4):179–189. doi: 10.1016/j.trsl.2008.12.009

Fig 5. Effect of treating mice with antibodies prior to hBOEC injection.

Fig 5

NOD/SCID mice were tail-vein injected with 50 μgrams anti-α4 integrin (Clone R1-2), anti-P-selectin (Clone RB40.34) and anti-E-selectin (Clone 10E 9.6) rat anti-mouse antibodies, normal rat IgG or with saline, 1 h prior to injection of 8×105 BOEC /mouse. Organs were harvested 3 hours later (8 mice per group). Error bars represent S.D. 5A) Lung: ** P<0.01for each test antibody compared to saline or control antibody. 5B) Bone Marrow: no significant changes. 5C) Spleen: anti-α4 integrin and anti E-selectin had *P<0.1 versus controls. Data confirmed by second experiment (not shown).