Table 7. The 20 most different cell surface markers based on fluorescent intensities.
| Assay panel | Cell surface marker | Trend | Autism (N = 70) | Typical Developing controls (N = 35) | P-Value | % Ratio | ||
| Mean | SD | Mean | SD | |||||
| Intensity Differences >31% | ||||||||
| CD16pCD66bpCD52n | CD52 | ↑ | 4453.5 | 1399 | 3395.8 | 1622.2 | 0.000 | 131 |
| CD4pnCD14pCD95p | CD95 | ↑ | 3632.8 | 1629.4 | 2764.9 | 705.8 | 0.002 | 131 |
| CD3pCD4nHLADRp | HLA-DR | ↑ | 2746 | 2019.5 | 2073.8 | 1281.9 | 0.020 | 132 |
| CD4pnCD14pCD25p | CD4 | ↑ | 254.2 | 189.5 | 193.6 | 196 | 0.040 | 131 |
| Intensity Differences 25–30% | ||||||||
| CD7pCD8pCD26p | CD26 | ↑ | 1149 | 390.5 | 887.4 | 202.4 | 0.000 | 129 |
| Neutrophil-CD66b | CD66b | ↑ | 4574.8 | 1275.6 | 3531.8 | 1310.6 | 0.000 | 130 |
| CD16pCD66bpCD52p | CD66b | ↑ | 4415 | 1392.3 | 3489 | 1284.5 | 0.002 | 127 |
| CD8pnCD57pCD94p | CD94 | ↑ | 1911.4 | 1016.2 | 1473.3 | 780.4 | 0.040 | 130 |
| Intensity Differences 21–25% | ||||||||
| CCR5nCD8pCD60n | CD8 | ↑ | 2278.5 | 479.4 | 1873.8 | 451.7 | 0.000 | 122 |
| CD8pCD20nCD38n | CD8 | ↑ | 2762.6 | 691 | 2285.8 | 612.5 | 0.001 | 121 |
| CD3pCD4pHLADRp | HLA-DR | ↑ | 1166.5 | 626.2 | 964.7 | 991 | 0.001 | 121 |
| CD8nCD16pCD101p | CD101 | ↓ | 970.5 | 439.5 | 1228 | 383.2 | 0.004 | 79 |
| CD11bpnCD16pnCD32p | CD32 | ↓ | 745.7 | 573.1 | 964.1 | 685.6 | 0.030 | 77 |
| CCR5pCD4pCD60p | CD4 | ↑ | 1594.7 | 920.9 | 1282.4 | 638.7 | 0.030 | 124 |
| Intensity Differences 16–20% | ||||||||
| CD8pCD45RApCD60p | CD8 | ↑ | 2717.3 | 462.1 | 2343.4 | 463.6 | 0.000 | 116 |
| CD8pCD20nCD95n | CD8 | ↑ | 2306 | 472.2 | 1981.9 | 404.1 | 0.001 | 116 |
| CD11bpCD16p | CD11b | ↑ | 2865.7 | 661.6 | 2390 | 691 | 0.001 | 120 |
| CD14nCD15pCD89p | CD15 | ↑ | 2478.2 | 619.4 | 2112.4 | 722 | 0.006 | 117 |
| CD16pnCD18pCD44p | CD44 | ↓ | 1654.1 | 740.3 | 2004 | 808.5 | 0.012 | 83 |
| CCR5pCD8pCD60n | CCR5 | ↑ | 856.6 | 324.1 | 739.8 | 232.6 | 0.030 | 116 |
Abbreviations: p = positive staining, n = negative staining, pn = weak positive staining, N = number. Univariate P value is shown to 3 decimal points only.
Ranking is based on intensity differences of 15% or more between autism and typically developing controls and statistical significance.