Table 4.
Death hazard ratio across the 4 quartiles of the Mental Health Dimension (upper panel) and Physical Health Dimension (lower panel) score in 705 maintenance hemodialysis patients
| Mental Health Quartiles | First Quartile (n = 177) | Second Quartile (n = 176) | Third Quartile (n = 177) | Fourth Quartile (n = 175) | Trend P |
|---|---|---|---|---|---|
| Unadjusted | 1.79 (1.27 to 2.51) | 1.60 (1.13 to 2.26) | 1.13 (0.79 to 1.63) | 1.00 (Reference) | <0.001 |
| P = 0.001 | P = 0.008 | P = 0.50 | |||
| Adjusteda (full) | 1.62 (1.12 to 2.34) | 1.66 (1.14 to 2.4) | 0.99 (0.66 to 1.5) | 1.00 (Reference) | 0.001 |
| P = 0.01 | P = 0.008 | P = 0.95 |
| Physical Health Quartiles | First Quartile (n = 176) | Second Quartile (n = 176) | Third Quartile (n = 177) | Fourth Quartile (n = 174) | Trend P |
|---|---|---|---|---|---|
| Unadjusted | 2.03 (1.44 to 2.84) | 1.59 (1.12 to 2.26) | 1.05 (0.72 to 1.53) | 1.00 (Reference) | <0.001 |
| P = 0.000 | P = 0.009 | P = 0.78 | |||
| Adjusteda (full model) | 1.45 (1.0 to 2.1) | 1.37 (0.93 to 2.0) | 1.00 (0.67 to 1.5) | 1.00 (Reference) | 0.008 |
| P = 0.05 | P = 0.11 | P = 1.0 |
Case-mix variables includes age, gender, race/ethnicity, diabetes, and log vintage. MICS variables includes values for albumin, creatinine, hemoglobin, total iron-binding capacity, normalized protein catabolic rate, lymphocyte percentage, and body mass index. CI, confidence interval; MICs, malnutrition-inflammation-cachexia syndrome.
a
Full model consists of case mix and MICS and logarithm of three inflammatory markers: C-reactive protein, IL6, and TNFα.