Table 3.
Relations of follow-up volume parameters with BP-related variables averaged over the preceding 4 months
| BP-Related Predictor Variable | Outcome |
|||||
|---|---|---|---|---|---|---|
| Vant (L) |
Vm (L) |
Vm/Vant (%) Controlling for Follow-Up Vant |
||||
| Regression Coefficient | 95% CI | Regression Coefficient | 95% CI | Regression Coefficient | 95% CI | |
| Predialysis systolic BP (per 10 mmHg increase) | 0.02 | (−0.01 to 0.04) | −0.00 | (−0.05 to 0.05) | −0.06 | (−0.22 to 0.09) |
| Predialysis diastolic BP (per 10 mmHg increase) | 0.05a | (0.01 to 0.09) | 0.08 | (−0.01 to 0.16) | 0.10 | (−0.15 to 0.35) |
| Postdialysis systolic BP (per 10 mmHg increase) | −0.08a | (−0.10 to −0.06) | 0.09a | (0.04 to 0.14) | 0.36a | (0.22 to 0.51) |
| Postdialysis diastolic BP (per 10 mmHg increase) | −0.04 | (−0.07 to −0.00) | 0.15a | (0.06 to 0.23) | 0.44a | (0.19 to 0.70) |
| Drop from predialysis to postdialysis systolic BP (per 10% greater drop) | 0.17a | (0.14 to 0.20) | −0.18a | (−0.26 to −0.09) | −0.80a | (−1.05 to −0.56) |
| Drop from predialysis to min. intradialytic systolic BP (per 10% greater drop) | 0.14a | (0.11 to 0.18) | −0.27a | (−0.37 to −0.18) | −1.06a | (−1.34 to −0.78) |
| Hypotensive episodes (≥1 episode versus 0 episodes) | 0.35a | (0.22 to 0.48) | −0.92a | (−1.26 to −0.58) | −0.43a | (−0.63 to −0.24) |
| Uft/Wt (per 10% increase) | −0.49a | (−0.80 to −0.19) | −1.50a | (−2.25 to −0.76) | −3.30a | (−4.29 to −2.31) |
Shown are results of separate time dependent mixed effects regression analyses relating follow-up volume parameters to individual follow-up BP-related predictor variables averaged over the preceding 4 months (not including the modeling session used to compute Vm or Vant) after controlling for baseline case mix factors, access type, and randomized treatment group. Analyses of Vant and Vm also controlled for baseline Vant
a
P < 0.01.