Table 1.
Baseline characteristics, USRDS adult Medicare primary kidney recipients with Medicare claims for influenza vaccination in the first post-transplant year transplanted from January 1, 2000 to July 31, 2006 followed through September 30, 2006
| Influenza Vaccination | All Others | P | |
|---|---|---|---|
| 9678 (18.7) | 42052 (81.3) | ||
| Transplant recipient factors | |||
| recipient age (years) | 54.94 ± 13.40 | 49.45 ± 13.73 | <0.001 |
| male gender (vs. female) | 5475 (56.6) | 25679 (61.1) | <0.001 |
| African-American race (vs. all others) | 1949 (20.1) | 13103 (31.2) | <0.001 |
| follow-up time in years | 3.07 ± 1.95 | 3.23 ± 1.94 | <0.001 |
| years on dialysis prior to transplant | 3.07 ± 2.65 | 3.53 ± 2.93 | <0.001 |
| peak PRA > 20% (31.0% missing) | 1261 (19.7) | 5927 (20.2) | 0.362 |
| delayed graft function (2.7% missing)a | 1491 (15.8) | 8463 (20.7) | <0.001 |
| diabetes (10.4% missing) | 2815 (32.2) | 10314 (27.4) | <0.001 |
| hypertension (10.3% missing) | 6876 (78.7) | 29044 (77.2) | 0.001 |
| ischemic heart disease (10.4% missing) | 1049 (12.0) | 2947 (7.8) | <0.001 |
| congestive heart failure (10.4% missing) | 1098 (12.6) | 4320 (11.5) | 0.004 |
| COPD (10.4% missing) | 167 (1.9) | 589 (1.6) | 0.023 |
| tobacco use (10.4% missing) | 364 (4.2) | 1752 (4.7) | 0.054 |
| cancer (10.4% missing) | 232 (2.7) | 581 (1.5) | <0.001 |
| HLA mismatches (2.1% missing) | 3.46 ± 1.80 | 3.61 ± 1.76 | <0.001 |
| Transplant donor factors | |||
| deceased donor | 6759 (69.8) | 30185 (71.8) | 0.004 |
| donor age >50 years | 2385 (24.6) | 9866 (23.5) | 0.014 |
| expanded criteria donorb | 3783 (39.1) | 16627 (39.5) | 0.419 |
| cold ischemia time >24 h | 826 (8.5) | 3783 (9.0) | 0.155 |
| Discharge immunosuppression | |||
| tacrolimus | 6331 (65.4) | 26088 (62.0) | <0.001 |
| cyclosporine (Neoral®) | 1920 (19.8) | 8639 (20.5) | 0.124 |
| mycophenolate | 7727 (79.8) | 31745 (75.5) | <0.001 |
| rapamycin | 1023 (10.6) | 5439 (12.9) | <0.001 |
| Induction immunosuppression | 7757 (80.2) | 33886 (80.6) | 0.340 |
| Year of transplant | <0.001 | ||
| 2000 to 2001 | 2357 (24.4) | 11388 (27.1) | |
| 2002 to 2003 | 2661 (27.5) | 12296 (29.2) | |
| 2004 to 2006 | 4660 (48.2) | 18368 (43.7) |
The data are presented as the means ± standard deviation for normally distributed continuous variables and N (%) for categorical variables. COPD, chronic obstructive pulmonary disease.
Delayed graft function indicates the need for dialysis within the first week after transplant.
Expanded criteria donor indicates a donor age of >50 years with history of two of the following (stroke, hypertension, creatinine >1.5 mg/dl) or donor age of >60 years.