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The Hh pathway is downregulated after curcumin treatment. Transcript levels of Hh pathway targets (Gli1 and Ptch1B) are reduced following treatment with nanocurcumin in DAOY (A) cells, but not in D283Med (B) or HSR-GBM1 (C). Protein levels of Bcl2 are downregulated following nanocurcumin treatment in DAOY cells (D). *p < 0.05, ***p < 0.001 compared to vehicle.
