Fig. 3.

Delayed-type hypersensitivity (DTH) responses of animals treated with chimeric A9H12. Cutaneous erythema diameter measured at the injection site after 40 UI or 2000 UI tuberculin-purified protein derivative (PPD) intradermal injections, repeated two to four times over a maximum of 18 weeks. (a,b) Two individual animals treated with 1 mg/kg chimeric A9H12. (c–e) Three individual animals treated with 0·1 mg/kg chimeric A9H12. Data are mean ± standard deviation of the diameter of each erythema measured over 8 days following the antigenic challenge, performed in duplicate and by two observers.