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. 2010 Jul 1;10(1):68–76. doi: 10.4161/cbt.10.1.12162

Figure 2.

Figure 2

Effects of SU11248 and compound C on AMPK-dependent ACC phosphorylation (P-ACC) and activating AMPK phosphorylation (P-AMPK) in WT MEFs, AMPK null MEFS, and LKB1 null MEFs cultured in complete medium. (A) Immunoblots of total protein from WT MEFs harvested following exposure to SU11248 (5 or 20 µM) or compound C (5 or 20 µM) for 6 h. (B) Immunoblots of total protein from WT and LKB1 null MEFs harvested following exposure to SU11248 (5 or 20 µM) or compound C (5 or 20 µM) for 6 h. Replicate blots were probed for the relative levels of P-ACC, total ACC, P-AMPK, or total AMPK. (C) Immunoblots of total protein from WT MEFs from (B) harvested following exposure to SU11248 (5 or 20 µM) or compound C (5 or 20 µM) for 6 h. Replicate blots were probed for the relative levels of P-CaMKI or total CaMKI.