Table 2.
Immunohistochemical and fluorescence in situ hybridization results.
| Histology | IHC | IHC | IHC | IHC | IHC | IHC | IHC | IHC | FISH | FISH |
|---|---|---|---|---|---|---|---|---|---|---|
| CCND1 (%) | CD34 | CD68 | S100 | keratin | P63 | SMA | vimentin | Split apart CCND1 | Split apart FUS | |
| Chondroid lipoma (n = 4) | ||||||||||
| Positive | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 |
| Focal positive | 0 | 0 | 1 | 2 | 2 | 0 | 0 | 0 | n.a. | n.a. |
| Negative | 0 | 4 | 3 | 1 | 2 | 4 | 4 | 1 | 4/4* | 4/4* |
|
| ||||||||||
| Myoepithelioma (n = 4) | ||||||||||
| Positive | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 0 |
| Focal positive | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | n.a. | n.a. |
| Negative | 2 | 4 | 3 | 0 | 0 | 3 | 4 | 0 | 4/4* | 3/3* |
|
| ||||||||||
| Lipoma (n = 21) | ||||||||||
| Positive | 0 | — | — | — | — | — | — | — | — | — |
| Focal positive | 16 (76) | — | — | — | — | — | — | — | — | — |
| Negative | 5 (24) | — | — | — | — | — | — | — | — | — |
|
| ||||||||||
| Well differentiated liposarcoma (n = 28) | ||||||||||
| Positive | 1 (4) | — | — | — | — | — | — | — | — | — |
| Focal positive | 16 (57) | — | — | — | — | — | — | — | — | — |
| Negative | 11 (39) | — | — | — | — | — | — | — | — | — |
|
| ||||||||||
| Myxoid liposarcoma (n = 18) | ||||||||||
| Positive | 0 | — | — | — | — | — | — | — | — | — |
| Focal positive | 0 | — | — | — | — | — | — | — | — | — |
| Negative | 18 (100) | — | — | — | — | — | — | — | — | — |
|
| ||||||||||
| Chondrosarcoma (n = 10) | ||||||||||
| Positive | 3 (30) | — | — | — | — | — | — | — | — | — |
| Focal positive | 3 (30) | — | — | — | — | — | — | — | — | — |
| Negative | 4 (40) | — | — | — | — | — | — | — | — | — |
*There were no translocations observed.
n.a.: not applicable.
IHC: immunohistochemical.