Table 1A.
Demographics and results of FoxO3 expression of the 24 bone marrow samples analyzed
| Diagnosis | Demographics | Pattern* |
| Ph+ALL | 54; male | C & N |
| Ph+ALL | 39; male | Negative |
| Ph+ALL | 76; male | N & C |
| Ph+ALL | 79; male | Negative |
| Ph+ALL | 41; male | Negative |
| Ph+ALL | 49; female | Negative |
| Ph+ALL | 19; male | Negative |
| Ph+ALL | 56; female | Negative |
| Ph+ALL | 28; male | Negative |
| Ph+ALL | 33; male | Negative |
| Ph+ALL | 65; female | Positive |
| Ph−ALL | 71; male | Positive; N |
| Ph−ALL | 79; female | Positive |
| Ph−ALL | 76; female | Positive |
| Ph−ALL | 66; male | Negative |
| Ph−ALL | 56; female | Positive; C & N |
| Ph−ALL | 61; male | Positive; C & N |
| Ph−ALL | 63; female | Negative |
| Ph−ALL | 64; female | Positive; C & N |
| Ph−ALL | 56; male | Positive; N |
| Control | 66; male; chronic anemia | Positive; N |
| Control | 73; female; thrombocytopenia, mild | Positive; N |
| Control | 58; male; non-Hodgkin Lymphoma | Positive; N |
| Control | 74; male; non-Hodgkin lymphoma | Positive; N |
FoxO3 is interpreted as positive, if >20% of cells show cytoplasmic or nuclear staining with FoxO3 antibody.
*
N, nuclear; C, cytoplasmic. Positive staining implies >20% cells/blasts staining positively (nuclear or cytoplasmic) for FoxO3. The 20% cut-off is similar to WHO criteria for blast counts and is a semi-arbitrary threshold for positive expression in bone marrow specimens.