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. Author manuscript; available in PMC: 2011 May 5.
Published in final edited form as: Biochem Pharmacol. 2001 Feb 15;61(4):467–476. doi: 10.1016/s0006-2952(00)00568-2

Fig. 5.

Fig. 5

Inhibition of growth of RNase H-overexpressing axenic amastigotes of L. amazonensis by anti-miniexon antisense S-oligo. Results are means ± SEM (N = 4). TbRH1+ and TbRH1− amastigotes incubated in parallel with 20 μM SSM had 2.3 × 107 and 2.2 × 107 cells/mL of culture medium, respectively. The numbers of amastigotes per milliliter of culture, when incubated without S-oligo or with 10 μM SSM, were very similar, and the differences were statistically insignificant. The differences of antisense activities of ASM between TbRH1+ and TbRH1− cells were statistically significant (P < 0.05).