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. Author manuscript; available in PMC: 2011 May 5.
Published in final edited form as: Biochem Pharmacol. 2001 Feb 15;61(4):467–476. doi: 10.1016/s0006-2952(00)00568-2

Fig. 6.

Fig. 6

Killing of RNase H-overexpressing L. amazonensis amastigotes by anti-miniexon antisense S-oligo inside macrophage phagolysosomes. Results are means ± SEM (N = 4). Macrophages incubated in parallel with 10 μM SSM had 546 ± 32 and 539 ± 22 amastigotes/100 cells, respectively, for TbRH1+ and TbRH1− cells. The numbers of amastigotes/100 macrophages incubated without S-oligo or with 5 μM SSM were very similar, and the differences were statistically insignificant. The differences of antisense activities of ASM between TbRH1+ and TbRH1− cells were statistically significant (P < 0.01).