Table 3.
Statistical analysis of survivor curves presented in Fig. 5 for flies overexpressing mouse MsrB2 and Drosophila MsrB and their controls.
| 1. Panel on Fig. 5 |
2. Genotype |
3. Sex |
4. Mean, days |
5. % vs driver/ w1118 |
6. Max, days |
7. % vs driver/ w1118 |
8. χ2 |
9. p > χ 2 |
|---|---|---|---|---|---|---|---|---|
| A | da-GAL4/w1118 N SY | F | 36.3 | −52 | 64.4 | −15 | 187.7 | <0.0001 |
| A | da-GAL4/w1118 DR SY | F | 69.2 | 76.1 | ||||
| B | da-GAL4/mMsrB23A | M | 44.7 | −5 | 51.8 | 0 | 12.7 | 0.0004 |
| B | da-GAL4/mMsrB22A | M | 49.7 | +6 | 59.9 | +16 | 35.99 | <0.0001 |
| B | da-GAL4/w1118 | M | 46.9 | 51.8 | ||||
| D | da-GAL4/dMsrB2A | M | 47.5 | −1 | 59.9 | +16 | 3.12 | 0.08 |
| D | da-GAL4/dMsrB2B | M | 46.2 | −1 | 54.5 | +5 | 0.75 | 0.39 |
| D | da-GAL4/w1118 | M | 46.9 | 51.8 | ||||
| C | elav-GAL4/mMsrB23A | F | 52.6 | −9 | 70.7 | 0 | 3.64 | 0.06 |
| C | elav-GAL4/mMsrB22A | F | 51.4 | −11 | 67.9 | −4 | 41.25 | <0.0001 |
| C | elav-GAL4/w1118 | F | 57.8 | 70.7 | ||||
| E | elav-GAL4/dMsrB2A | F | 54.2 | −6 | 67.1 | −5 | 49.7 | 0.02 |
| E | elav-GAL4/dMsrB2B | F | 55.0 | −5 | 70.7 | 0 | 4.7 | 0.26 |
| E | elav-GAL4/w1118 | F | 57.8 | 70.7 |
Column 1 indicates panel in Fig. 5. The genotypes and gender (female, F; males, M) of flies are shown in columns 2 and 3, respectively. The mean lifespan is indicated in column 4 and percent change in the mean lifespan compared with their genetically matched controls (GAL4-driver/w1118) is displayed in column 5. Maximum lifespan and percent change of the maximum lifespan are shown in columns 6 and 7, respectively. Comparison of two types (transgenic and control) of survivor curves (three curves in each group, 210 flies for panels B, D and 105 flies for other panels) was performed with SAS software (see Section 2.12). Statistics of non-parametrical log rank test (χ2) is shown in column 8; p-value in column 9.