Table 4.
In vitro and in vivo competition index of selected mutants
| Gene | Function of product | Fold change in expression | P value | q value | CIa,b |
|
|---|---|---|---|---|---|---|
| In vitro | In vivo | |||||
| dnaK | Chaperone protein | 7.17442 | 0.001626 | 0.033028 | 0.88 (0.23–0.46) | 0.43 (0.08–0.11) |
| dnaJ | Chaperone protein | 4.08406 | 0.001597 | 0.032868 | 0.91 (0.19–0.33) | 0.50 (0.13–0.25) |
| phoP | Response regulator in TCSc | 3.690768 | 0.009174 | 0.065915 | 0.76 (0.29–0.46) | 0.23 (0–0.35) |
| ybtA | Regulator | 7.828241 | 1.06E-05 | 0.00089 | 1.03 (0.24–0.68) | 0.35 (0–0.28) |
a
CI, competitive index. Values > 1 indicate that the mutant outcompeted the wild type; values < 1 indicate that the wild type outcompeted the mutant.
b
Values are the mean CI values obtained from 5 to 10 chicks each, along with upper and lower confidence limits. Values in bold are significant from 1 (P < 0.05).
c
TCS, two-component signal transduction system.