Table 3.
Defective ability of plzA mutant to survive in ticks and to be transmitted to naïve mice based on tick immersion studies
| Type of strain | % of fed ticks positive for B. burgdorferi | No. of spirochetes/tick | No. of mice infected/total |
|---|---|---|---|
| Wild type | 80 | 3,100 ± 1,125 | 2/2 |
| plzA mutant | 80 | 330 ± 183 | 0/2 |
| Complemented plzA+ | 41 | 5,600 ± 4,869 | 2/2 |