Table 1.
Predictors of splenomegaly and hepatomegaly
| Condition | Analysis (n) | Predictor | r2 | Standardized β coefficient | P value |
|---|---|---|---|---|---|
| Splenomegaly | 8-wk infection (10) | Hydroxyproline | 0.514 | +0.717 | 0.020 |
| 12-wk infection (10) | Hydroxyproline | 0.825 | +0.908 | 0.000 | |
| Cytokeratin 18 | 0.120 | +0.437 | 0.006 | ||
| 20-wk infection (10) | MUP | 0.849 | −0.535 | 0.006 | |
| Hydroxyproline | 0.099 | +0.497 | 0.008 | ||
| 20-wk infection independent of hydroxyproline (10) | MUP | 0.849 | −0.922 | 0.000 | |
| Independent of time of infection (35) | Hydroxyproline | 0.757 | +0.657 | 0.000 | |
| Peroxiredoxin 6 | 0.051 | −0.295 | 0.000 | ||
| MUP | 0.045 | −0.277 | 0.004 | ||
| Independent of time of infection and hydroxyproline (35) | IL-2 | 0.477 | +0.294 | 0.032 | |
| MUP | 0.111 | −0.503 | 0.000 | ||
| Peroxiredoxin 6 | 0.063 | −0.330 | 0.008 | ||
| Hepatomegaly | 8-wk infection (10) | Hydroxyproline | 0.478 | +0.692 | 0.027 |
| 12-wk infection (10) | Hydroxyproline | 0.822 | +0.799 | 0.000 | |
| 20-wk infection (10) | S. mansoni PEPCK | 0.541 | +0.736 | 0.015 | |
| 20-wk infection independent of hydroxyproline (10) | MUP | 0.452 | −0.673 | 0.033 | |
| Independent of time of infection (35) | Hydroxyproline | 0.455 | +0.623 | 0.000 | |
| Peroxiredoxin 6 | 0.095 | −0.313 | 0.012 | ||
| Independent of time of infection and hydroxyproline (35) | IL-2 | 0.430 | +0.656 | 0.000 |