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. 2011 May;55(5):2224–2232. doi: 10.1128/AAC.01477-10

Table 2.

Effects of MLs and Pgp modulators on transport activity of Pgp in nematodes and mammalian cells

Compound Effluxa
Reference(s)
Nematodesb Mammalian cellsc
Selamectin + 19
Emamectin + ?
Hoechst + + 61
Vinblastine + 61
Daunorubicin + 61
Albendazole (+) 0 41
Doramectin + ?
Eprinomectin + ?
Levamisole + 0 14, 25
Moxidectin + (−) 46
Colchicine + + 61
Abamectin + 13
Ivermectin 0 13, 45, 57
Thiabendazole 0 21
Verapamil 16, 26, 54
a

+, increased efflux; −, decreased efflux; (+) or (−), low-level increased or decreased efflux.

b

Results from the present study.

c

Results from the literature.