Table 3.

Substituents in MLs^a

ML	Substituent at C-5	Sugar at C-13	Bond at C-22–C-23	Substituent at C-25
Ivermectin	Hydroxyl	α-l-Arabino-hexapyranosyl	Single	Isopropyl/sec-butyl
		α-l-Arabino-hexapyranosyl
Abamectin	Hydroxyl	α-l-Arabino-hexapyranosyl	Double	Isopropyl/sec-butyl
		α-l-Arabino-hexapyranosyl
Moxidectin	Hydroxyl	No sugar	Single + oxime or methoxyimino?	Dimethyl-butenyl
Eprinomectin	Hydroxyl	α-l-Lyxo-hexapyranosyl	Double	Isopropyl/sec-butyl
		α-l-Arabino-hexapyranosyl
Doramectin	Hydroxyl	α-l-Arabino-hexapyranosyl	Double	Cyclohexyl
		α-l-Arabino-hexapyranosyl
Emamectin	Hydroxyl	α-l-Lyxo-hexapyranosyl	Double	Isopropyl/sec-butyl
		α-l-Arabino-hexapyranosyl
Selamectin	Ketoxime	α-l-Arabino-hexapyranosyl	Single	Cyclohexyl

^aThe main differences are shown in bold.