Table 1.

Amino acid sequences of designed peptides

Peptide	Amino acid sequence	Length (residues)	Charge	ΔPhe	Trp	MW (calculated)	MW (observed)
VS1	Ac-K-A-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH	11	+4	3	1	1,466.8	1,468
Series I (analogs with variable length)
VSL1	Ac-ΔF-K-A-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH2	12	+4	4	1	1,607.4	1,608
VSL2	Ac-A-ΔF -K-A-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH2	13	+4	4	1	1,679.8	1,679
VSL3	Ac-K-A-ΔF-K-A-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH2	14	+5	4	1	1,807.3	1,808.2
Series II (analogs with different Trp contents)
VS2	Ac-K-W-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH2	11	+4	3	2	1,577.6	1,575.1
VS3	Ac-K-W-ΔF-W-K-ΔF-W-K-ΔF-V-K-NH2	11	+4	3	3	1,665.7	1,667
VS4	Ac-K-W-ΔF-W-K-ΔF-W-K-ΔF-W-K-NH2	11	+4	3	4	1,752.4	1,754.7
Series III (branched dimeric analog)
VSD1	Ac-K-A-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH\K	23	+8	6	2	3,001	3,000.6
	Ac-K-A-ΔF-W-K-ΔF-V-K-ΔF-V-K-NH/