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MICs of peptide analogs against Gram-negative (E. coli ML35p) and Gram-positive (S. aureus 700699) bacteria
| Peptidea | MIC (μM)b |
|
|---|---|---|
| E. coli ML35p | S. aureus (ATCC 700699) | |
| VS1 | 25 | >50 |
| Series I | ||
| VSL1 | 5 | 50 |
| VSL2 | 5 | >50 |
| VSL3 | 5 | >50 |
| Series II | ||
| VS2 | 5 | 50 |
| VS3 | 5 | 25 |
| VS4 | 5 | 10 |
| Series III | ||
| VSD1 | 1 | 5 |
| Rifampin | 5 | 1 |
| Kanamycin | 4 | 7.5 |
Rifampin and kanamycin were taken as reference antibiotics.
MICs are shown as the geometric means of three sets of determinations.
