Table 1.
Ratios of anidulafungin concentrations in pleural fluid and serum
Time (h) | Anidulafungin concn (μg/ml) in: |
Pleural fluid/serum drug concn ratioa | |
---|---|---|---|
Pleural fluid | Serum | ||
0 | 4.63 | ||
1.95 | 0.88 | 0.102 | |
2.0 | 8.61 | ||
3.97 | 7.44 | 0.090 | |
4.0 | 0.67 | ||
5.93 | 0.87 | ||
8.93 | 6.36 | 0.119 | |
8.98 | 0.76 | ||
21.0 | 0.78 | ||
21.75 | 4.07 |
Ratios reflect the values obtained for the two sample sources at the closest time points of collection.