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. 2011 May;55(5):1930–1936. doi: 10.1128/AAC.01520-10

Fig. 4.

Fig. 4.

Histopathologic examination of liver steatosis in Himalayan marmots treated with metacavir (PNA), zidovudine (AZT), or water for 90 days (hematoxylin and eosin [H&E] staining; magnification, ×400). (A) Control group (normal). (B) Group treated with AZT at 100 mg/kg/day, showing severe microvesicular steatosis of more than 90% hepatocytes. (C) Group treated with PNA at 100 mg/kg/day, showing mild steatosis of fewer than 20% of hepatocytes. (D) Group treated with PNA at 50 mg/kg/day (normal).