Table 2.

Activities of antimicrobial agents against 17 clinical isolates of unusual Nocardia species

Antimicrobial agent	MIC (μg/ml)a for:
	N. flavorosea (5)	N. abscessus (3)	N. carnea (2)	N. alba (1)	N. asteroids complex (1)	N. elegans (1)	N. jinanesis (1)	N. transvalensis (1)	N. rhamnosiphila (1)	N. takedensis (1)
Amoxicillin-clavulanic acid	4–16 (60)	1–32 (67)	32 (0)	2 (S)	64 (R)	16 (R)	8 (S)	8 (S)	8 (S)	1 (S)
Cefoxitin	0.12–16	1–16	1–16	2	32	4	8	8	4	1
Ceftriaxone	0.25–8 (100)	0.5–2 (100)	2–4 (100)	2 (S)	8 (S)	4 (S)	2 (S)	4 (S)	1 (S)	2 (S)
Meropenem	1–4	1–4	1	0.25	2	0.12	2	4	1	2
Ertapenem	2–8	1–8	0.5–2	1	2	0.25	4	16	2	2
Imipenem	0.5–2 (100)	0.25–1 (100)	0.25–0.5 (100)	1 (S)	1 (S)	0.12 (S)	0.5 (S)	32 (R)	0.5 (S)	1 (S)
Doripenem	1–4	0.25–4	1	0.25	2	0.12	2	2	1	2
Azithromycin	>128	32–>128	16–>128	16	128	1	128	32	>128	32
Ciprofloxacin	4–16 (0)	4–128 (0)	0.25 (100)	2 (R)	16 (R)	16 (R)	8 (R)	1 (S)	1 (S)	4
Nemonoxacin	0.25–1	0.5–16	0.12	1	1	1	1	0.25	0.12	0.25
Gemifloxacin	2–4	0.5–32	0.03–0.06	1	2	2	2	1	0.12	0.5
Levofloxacin	8–16	2–>32	0.25–0.5	8	4	16	8	0.5	2	4
Moxifloxacin	2–4	2–32	0.25	4	2	4	2	0.25	0.5	1
Linezolid	2–4 (100)	0.5–2 (100)	0.5–2 (100)	2 (S)	4 (S)	2 (S)	4 (S)	1 (S)	2 (S)	4 (S)
Vancomycin	16–>128	0.25–128	128	0.25	16	32	128	>128	128	128
Daptomycin	128–>128	0.5–128	128–>128	1	128	>128	128	>128	128	128
Sulfamethoxazole	4–8 (100)	8 (100)	4–8 (100)	32 (S)	4 (S)	8 (S)	4 (S)	32 (S)	4 (S)	4 (S)
Amikacin	0.5–4 (100)	0.12–4 (100)	0.12–0.25 (100)	0.25 (S)	0.5 (S)	0.25 (S)	0.5 (S)	32 (R)	0.25 (S)	1 (S)
Tigecycline	0.5–2	0.12–2	0.5–1	0.06	1	2	4	2	0.25	0.25

^aThe MIC range is shown, with the percentage of susceptible isolates or susceptibility category (S, susceptible; I, intermediate; R, resistant) in parentheses. The number of isolates for each species is shown in parentheses.