Fig. 3.

Inhibition of P2-mediated adenosine transport by furamidine analogues. Transport of 0.050 μM [³H]adenosine was assessed in the presence and absence of various concentrations of DB075 (▾), DB820 (○), and CPD0801 (Δ) over a period of 30 s. Uptake was determined in the presence of 1 mM inosine, which does not inhibit P2-mediated [³H]adenosine transport but does competitively inhibit P1-mediated uptake (15). The data are representative of the results of at least three similar experiments, each performed in triplicate. Bars represent SEM.