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Bacterial lung load from mice treated with PBS or IVIG and P4. Lung titers were determined for groups of influenza-virus-and-pneumococcus-coinfected mice (n = 5) either mock treated with PBS or treated with IVIG and P4 peptide 48 and 72 h after bacterial challenge. Values indicate the mean, and error bars the standard deviation of the measurements. An asterisk indicates a significant (P < 0.05) difference in bacterial titer compared to mock-treated animals at that time point.
