Table 1.
Yr | Clinical form | Underlying condition | Diagnosis | Antifungal treatment | Outcome | Patient with mutant isolatesb |
---|---|---|---|---|---|---|
2001 | Pericarditis and adenopathies | HIV | Proven | Amphotericin B | Poor | D |
2001 | Pulmonary | Hematological cancer | Probable | Amphotericin B | Poor | E |
2002 | Postsurgical | Surgery | Probable | Itraconazole | Survival | |
2002 | Pulmonary | COPDa | Probable | Amphotericin B | Poor | |
2003 | Postsurgical | Surgery | Probable | Itraconazole | Survival | |
2003 | Pulmonary | COPD | Probable | Caspofungin | Poor | |
2006 | Postsurgical mediastinitis | Surgery | Proven | Voriconazole + caspofungin | Poor | B |
2006 | Pulmonary | COPD | Probable | Voriconazole | Survival | |
2007 | Pulmonary | COPD | Probable | Voriconazole | Survival | |
2007 | Pulmonary | COPD | Probable | Voriconazole | Survival |
COPD, chronic obstructive pulmonary disease.
Patients infected with isolates harboring mutations in the cyp51A gene are identified by an alphabetical code.