Fig. 2.
(a to c) LC-MS analysis of the extract of Schistosoma mansoni treated with trioxaquine PA1259 (50 μg/ml). Extracted ionic current (EIC) traces for heme (heme, M+) (a), “complete” heme-PA1259 adducts 1 and/or 2 (MH+/2) (b), and heme-PA1259 adduct 3 (MH+) (c). (The insets at the right show the mass spectra of chromatographic peaks with arrows.)