Table 4.

Summary of multivariable logistic regression models for factors associated with mycological success

Model description	Independent variable	Estimated	Odds ratio (95% CI)	P value
Model 1, with AUC/MIC ratio evaluated as	APACHE II score ≤ 11a	0.883	2.42 (1.16, 5.05)	0.019
an independent variable	AUC/MIC ratio ≤ 3,000b	−0.353	0.702 (0.362, 1.36)	0.30
	3,000 < AUC/MIC ratio ≤ 12,000b	1.89	6.60 (1.54, 28.3)	0.011
	History of corticosteroid use	−0.720	0.487 (0.256, 0.925)	0.028
Model 2, with MIC evaluated as an	APACHE II score ≤ 11a	0.945	2.57 (1.23, 5.38)	0.012
independent variable	History of corticosteroid use	−0.686	0.504 (0.267, 0.951)	0.034
	MIC < 0.5 mg/literc	0.819	2.27 (1.07, 4.81)	0.033
Model 3, non-C. parapsilosis population with	APACHE II score ≤ 11a	0.853	2.35 (0.993, 5.54)	0.052
AUC/MIC ratio evaluated as an	AUC/MIC ratio < 5,000b	−0.210	0.811 (0.312, 2.11)	0.67
independent variable	5,000 < AUC/MIC ratio ≤ 12,000b	1.84	6.27 (1.46, 27.0)	0.014
	History of corticosteroid use	−0.712	0.491 (0.241, 0.998)	0.05

^aReference group for APACHE II score is >11.

^bReference group for AUC/MIC ratio is >12,000.

^cReference group for MIC is ≥0.5 mg/liter.

^dThe intercepts for the logistic regression function describing the multivariable models 1, 2, and 3 are 1.97, 1.37, and 1.97, respectively.