Table 2.

The effects of the 5-HT_2A receptor F340^6.52L mutation on ligand affinity.

Compound	KI (nM)a
	Wild type	F340L
1a	20	57
1b	1.3	1.8
4a	4,610	4,140
4b	260	3.5
DOI	0.92	13,700
ketanserin	0.4	0.23

^a[³H]Ketanserin labeled cloned 5-HT_2A sites.

K_i values at the wild type receptors are from Table 1.

Standard errors typically range between 15–25% of the K_i value.