Figure 3.

Illustration of the differences in binding site residue composition of the hH1 and h5-HT2A receptors within the context of the β2AR-T4L crystal structure. Residues are truncated at the Cβ carbon atom (ball-and-stick representation) and are colored based on residue similarity as described in Fig. 2. For those positions whose residue identity differs, the H1 residue is listed first, followed by the 5-HT2A residue.