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. Author manuscript; available in PMC: 2011 May 5.
Published in final edited form as: J Biol Chem. 2007 Mar 27;282(19):14186–14193. doi: 10.1074/jbc.M700827200

FIGURE 6. Proposed involvement of ETC in PQ2+-dependent H2O2 generation in brain mitochondria.

FIGURE 6

Electrons feed into the ETC at the level of complex I or complex II and are transferred to ubiquinone (CoQ), complex cytochrome c (c), and complex IV sequentially. Complex III has the ability transfer these electrons to PQ2+, thus forming the PQ+· radical, leading ROS formation and subsequent cell damage.