Table III.
Frequency of positive responses to individual ZnT8 peptide pools (all subjects).
pool | % control | % T1D | p | |
---|---|---|---|---|
1 | 2.4 | 40.0 | < 0.0001 | *** |
2 | 2.4 | 25.7 | 0.0044 | ** |
3 | 0.0 | 14.3 | 0.0176 | * |
4 | 9.8 | 20.0 | 0.3272 | NS |
5 | 4.9 | 37.1 | 0.0005 | *** |
6 | 14.6 | 28.6 | 0.1655 | NS |
7 | 17.1 | 40.0 | 0.0389 | * |
8 | 4.9 | 28.6 | 0.0093 | ** |
9 | 9.8 | 45.7 | 0.0005 | *** |
10 | 14.6 | 42.9 | 0.0095 | ** |
11 | 24.4 | 31.4 | 0.6086 | NS |
12 | 4.9 | 11.4 | 0.4052 | NS |
13 | 14.6 | 22.9 | 0.3889 | NS |
14 | 12.2 | 40.0 | 0.0075 | ** |
15 | 7.3 | 25.7 | 0.0550 | NS |
16 | 4.9 | 31.4 | 0.0044 | ** |
17 | 4.9 | 57.1 | < 0.0001 | *** |
18 | 0.0 | 31.4 | < 0.0001 | *** |
19 | 2.4 | 34.3 | 0.0003 | *** |
20 | 7.3 | 22.9 | 0.0991 | NS |
21 | 9.8 | 48.6 | 0.0002 | *** |
22 | 19.5 | 28.6 | 0.4224 | NS |
23 | 12.2 | 28.6 | 0.0892 | NS |
Data are the percentages of the control group (n = 41) and T1D group (n= 35) who responded (SI ≥ 3) to a particular ZnT8 peptide pool. Statistical comparisons used Fischer’s exact test. NS not significant;
p < 0.05;
p < 0.01;
p < 0.001.