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. 2011 Apr 25;52(5):2749–2757. doi: 10.1167/iovs.10-6631

Table 3.

Three-Year Change in Spherical Equivalent Refractive Error According to Baseline Characteristics

Baseline Characteristic Change in Average Spherical Equivalent between Baseline and 3 Years (D)
Estimated Difference, Adjusted for Baseline Spherical Equivalent P for Interaction
SVL
PAL
n Mean n Mean
Age, y 0.92*
    8 to <9 13 −1.39 8 −1.23 0.18
    9 to <10 17 −1.14 13 −1.11 0.11
    10 to <11 14 −1.19 15 −0.71 0.48
    11 to <12 14 −0.88 16 −0.64 0.26
Sex 0.52
    Male 31 −1.09 19 −0.95 0.20
    Female 27 −1.21 33 −0.82 0.39
Race/Ethnicity 0.94
    White 30 −1.10 26 −0.79 0.32
    Nonwhite 28 −1.19 26 −0.94 0.30
Prior spectacle wear (SVLs) 0.48
    Currently or in past 34 −1.10 31 −0.90 0.22
    Never 24 −1.22 21 −0.81 0.42
Spherical equivalent, D 0.24/0.57
    −0.75 to −1.49 33 −1.20 25 −0.79 0.35
    −1.50 to −2.50 25 −1.08 27 −0.93 0.17
Accommodative lag, D 0.23/0.55
    0.50 to 1.49 38 −1.12 28 −0.91 0.24
    1.50 or worse 20 −1.20 24 −0.81 0.41
Near esophoria, PD 0.56
    2 to 5 33 −1.13 30 −0.97 0.18
    6 to 10 21 −1.09 18 −0.66 0.46
    >10 4 −1.60 4 −1.01 0.63
Parental history of myopia 0.43
    Neither parent 5 −0.72 9 −0.83 −0.10
    One parent 10 −1.28 15 −0.73 0.57
    Both parents 20 −1.29 18 −0.99 0.30
*

Corresponds to the interaction between treatment and the continuous variable.

The first P value tests for the interaction between treatment and age as a continuous variable; the second P value tests for the interaction between treatment and the two-level categorical variable.