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. 2011 Apr 18;108(18):7589–7594. doi: 10.1073/pnas.1016232108

Fig. 5.

Fig. 5.

pitp-1 and DAG signaling interact downstream of sensory transduction.(A and B) Effect of dgk-1(sy428) mutation on chemotaxis to salt (A) and benzaldehyde (B), under pitp-1(tm1500) mutant background. Error bars represent SEM. **P < 0.001, +P < 0.05, Tukey test. (C and D) Structure-function analysis of PITP-1. Schematic representation of pitp-1 deletion constructs tagged with Venus (C) and the results of rescue experiments (D). The pitp-1 promoter was used to express the deletion constructs of pitp-1. Error bars represent SEM. **P < 0.001, Dunnett test. (E) Model for PITP-1 function in ASER. PITP-1 transports PtdIns to the presynaptic membrane and promotes salt attraction via DAG production and plasticity of salt chemotaxis through unknown signals derived from PtdIns.