Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 May 5;6(5):e17561. doi: 10.1371/journal.pone.0017561

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Watson et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A. Group A contains camptothecin analogues used in primary screen. Camptothecin analogues in Group B were used in the validation screen. Camptothecins in Group A/B were rerun from the primary and secondary screens. Each chromosome was partitioned into 10 cM regions. B. Each drug-dose combination that resulted in a significant QTL (LOD>threshold value) is indicated in blue. Intensity of the shading indicates the number of doses replicating that QTL at either the suggestive or significant level. Regions which also had a suggestive QTL (LOD>suggestive threshold) are indicated in green with color intensity referring to the number of doses replicating this peak.