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. 2011 May 5;6(5):e19518. doi: 10.1371/journal.pone.0019518

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Kong et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The relative expression of miR-29a for 6-month-old p21-HBx transgenic mice versus WT mice was detected by qRT-PCR. (B) The expression of miR-29a in stable HBx-transfected hepatoma cell lines was examined by qRT-PCR. (C) The expression levels of miR-29a in HepG2-X (or H7402-X) were examined by qRT-PCR after treatment with HBx RNAi in a dose dependent manner. (D) The relative expression level of miR-29a in HepG2.2.15 cells was examined by qRT-PCR. Plotted are the means ± SD of three samples normalized to U6. Statistically significant differences, arbitrarily set to 1.0, are indicated: *P<.05, **P<.01, Student's t test.