Figure 1. Effect of drugs on overall contractile activity.

A) Example spatiotemporal maps highlight the different types of contractions and different number of contractions observed. The light colour represents contractions. The arrows point to contractions were AWL represents anally propagating whole-length contractions, ASL represents anally propagating short-length contractions, OSL represents orally propagating short-length contractions and stat represents stationary contractions, B) Total contraction counts during 20-minute video recordings for control and for each pharmacological agent. Asterisks indicate a significant difference in the number of contractions between drug and control recordings (determined by unpaired t-tests, p<0.05).