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. Author manuscript; available in PMC: 2011 May 5.
Published in final edited form as: World J Surg. 2009 Nov;33(11):2452–2457. doi: 10.1007/s00268-009-0175-3

Fig. 5.

Fig. 5

Inhibition of the PI3K-Akt pathway causes apoptosis. PC-12 cells were treated with the indicated concentrations of LY294002 for 2 days, and total cell lysates were prepared. An increase in the cleavage of poly-ADP ribose phosphate (PARP) and caspase-3 suggests that apoptosis induced cell death. GAPDH was used as a loading control. PARP