Table 7.

Example Table: Net reclassification improvement based on addition of gene count score to Framingham offspring risk score

Framingham offspring risk score	Framingham offspring risk score plus gene count score				Reclassified		Net correctly reclassified
	<5%	5–10%	10–15%	>15%	Increased risk	Decreased risk
People without diabetes during follow-up
<5%	2,295	48	0	0
5–10%	36	482	43	0	121	64	−1.7%
10–15%	0	19	181	30
>15%	0	0	9	181
People with diabetes during follow-up
<5%	52	8	0	0
5–10%	2	37	3	0	14	11	1.5%
10–15%	0	4	24	3
>15%	0	0	5	64

Adapted from [52]

Net reclassification improvement −0.2% (95% CI −5.1 to 4.7); P = 0.94