TABLE 1.
Experiment 1: regimen of immunization of group 1 by priming with plasmid DNA and boosting with recombinant MVA
| Immunizations received | Animala | DNA (mg) administered at wk 0 | PFU of virus administeredb at wk:
|
||
|---|---|---|---|---|---|
| 4 | 24 | 72 | |||
| pSG2-85A and MVA-85A (test) | BT37 | 2 i.d., 2 i.m. | 5 × 108 i.v. | 109 i.v. | 109 i.v. |
| BT99 | 2 i.d., 2 i.m. | 5 × 108 i.d. | 109 i.d. | 109 i.d. | |
| pSG2 and MVA (control) | BT53 | 2 i.d., 2 i.m. | 5 × 108 i.v. | 109 i.v. | Not done |
| BT47 | 2 i.d., 2 i.m. | 5 × 108 i.d. | 109 i.d. | Not done | |
a
Animal BT53 was female; the others in this group were male.
b
i.v., intravenously.