MAb-mediated opsonophagocytic killing of type 8 pneumococci. The numbers of CFU resulting from the incubation of type 8 cells with human PMNs, D11, NAD, or isotype controls were compared in an opsonophagocytic killing assay, as shown on the y axis, for each of the concentrations of HS shown on the x axis. No statistical differences were detected (one-way ANOVA). HS contains intact classical and alternative complement pathways. P, type 8 pneumococci; P/PMN, type 8 pneumococci and human PMNs.