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PANTHER analyses of c-Kit (downregulated genes by imatinib treatment) versus NGF-regulated genes which are involved in immune related function in HMC-1 (V560G c-Kit) cells (selected).
| PANTHER Protein Class | V560G c-KIT (P-value) | NGF-TrkA (P-value) |
|---|---|---|
| Cytokine | 2.45E-06 | 3.33E-03 |
| Cytokine/interleukin superfamily | 6.74E-05 | 2.15E-02 |
| Receptor | 1.17E-04 | NS |
| Receptor/cytokine receptor | 6.65E-04 | NS |
| receptor /type I cytokine receptor | 3.81E-03 | NS |
| Esterase | 2.10E-03 | NS |
NS: not significant
