TABLE 1.
Dosea | CFU
(106)b
|
||
---|---|---|---|
Control | CpG ODN | non-CpG ODN | |
First | 2.5 ± 0.8 | 1.5 ± 0.1 | NDc |
Second | 2.5 ± 0.08 | 1.2 ± 0.04d | 3.3 ± 0.05 |
Mice were infected with H. pylori SS1, and 2 weeks later were given CpG ODN or non-CpG ODN or were left untreated (control). Three days after each dose mice were sacrificed, and the bacterial loads were quantified as described in Materials and Methods.
The data are geometric means ± standard errors of the means for each treatment group containing eight or nine mice.
ND, not determined.
P < 0.01 compared to control untreated mice.