Table 2.
Temperature, Arterial Blood Gas, and Electrolyte Values in the Three Study Groups
|
Groups |
Control |
ICP-CPP |
MAP-CPP |
|||
|---|---|---|---|---|---|---|
| Variable | Mean | SEM | Mean | SEM | Mean | SEM |
| Rectal temperature (°C) | 37.2 | 1.1 | 37.4 | 1.2 | 36.9 | 1.5 |
| Cranial temperature (°C) | 35.6 | 1.5 | 35.4 | 1.3 | 35.8 | 1.6 |
| Glucose (mg/dL) | 246.5 | 20.5 | 254 | 31.23 | 230.33 | 54.57 |
| Na (mM/L) | 135.6 | 0.68 | 136.75 | 2.14 | 137.67 | 0.88 |
| K (mM/L) | 5.54 | 0.22 | 5.2 | 0.29 | 5.03 | 0.98 |
| Total CO2 (mM/L) | 22.17 | 0.87 | 19.75 | 2.14 | 21 | 5.69 |
| iCa (mM/L) | 1.39 | 0.04 | 1.31 | 0.03 | 1.31 | 0.068 |
| Hematocrit (% PCV) | 41.8 | 0.86 | 39 | 3.11 | 42.33 | 0.88 |
| Hemoglobin (g/dL) | 13.25 | 1.05 | 13.25 | 1.05 | 14.4 | 0.32 |
| pH | 7.39 | 0.015 | 7.39 | 0.048 | 7.21 | 0.03 |
| PCO2 (mm Hg) | 37.39 | 2.27 | 39.3 | 2.53 | 48.6 | 12.31 |
| PO2 (mm Hg) | 121 | 17.62 | 116.75 | 14.69 | 121 | 17.62 |
| HCO3 (mM/L) | 21.97 | 2.77 | 18.95 | 2.14 | 19.7 | 5.37 |
| BEecf (mM/L) | −3.57 | 0.81 | −4.43 | 2.94 | −4.33 | 5.89 |
| Oxygen saturation (%) | 99 | 0.29 | 99.1 | 0.25 | 98.7 | 0. 27 |
Data presented as a mean±SEM of three blood samples per animal taken at CPP of 70, 50, and 30 mm Hg or at the appropriate time points in the control group (n=10 rats per group).
ICP, intracranial pressure; MAP, mean arterial pressure; CPP, cerebral perfusion pressure; SEM, standard error of the mean; PCO2, partial arterial carbon dioxide pressure; PO2, partial arterial oxygen pressure; PCV, packed cell volume; iCa, ionized calcium; BEecf, base excess in extracellular fluid.