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. 2003 Dec;71(12):7035–7042. doi: 10.1128/IAI.71.12.7035-7042.2003

FIG. 2.

FIG. 2.

Proliferative responses of leukocyte-rich guinea pig cell populations. BAL cells (A), SPC (B), and PC (C) from both unvaccinated (open bars) and BCG-vaccinated (closed bars) guinea pigs were prepared as described in the text and incubated for 4 days in the presence of mitogenic stimuli (ConA or LPS) or mycobacterium-specific stimuli, including a live attenuated (H37Ra) or virulent (H37Rv) strain of M. tuberculosis at an infectivity ratio of 1:100 or hkRv. The SI is defined as the ratio of counts per minute of tritiated thymidine taken up by stimulated cells to counts per minute of unstimulated cells from the same source. Results are given as the means ± standard errors of the means for four animals per group. Differences between the vaccination groups were compared by Student's t test, assuming equal variances. P values of <0.05 (*) were considered significant.