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. Author manuscript; available in PMC: 2012 Apr 5.
Published in final edited form as: Biochemistry. 2011 Feb 28;50(13):2550–2558. doi: 10.1021/bi1020106

Figure 7. The rate determining process in lipidation of apoE.

Figure 7

The kinetics of lipidation of 100 nM apoE4. The solid line is calculated using the rate constants listed in Table 1 for apoE4. The other kinetic plots are calculated assuming a 33% variation in the values of or k-2 (A) or k-1 (B) or k+c (C). It can be seen that dissociation rate constant of dimer to monomer (k-1) has the maximum effect on the overall rate. The kinetic traces are generated using Kintek Explorer (38).