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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Hepatology. 2011 Apr;53(4):1377–1387. doi: 10.1002/hep.24229

TABLE 3.

COMMON DRUGS CAUSING VARIOUS DRUG INDUCED CHOLESTATIC SYNDROMES

Cholestasis without Hepatitis
Cholestasis with Hepatitis
Cholestasis with Bile Duct Injury
Vanishing Bile Duct Syndrome (Ductopenia)
Sclerosing Cholangitis like cholestasis
Anabolic steroids Estrogens Tamoxifen Azathioprine Cyclosporine Nevirapine Glimepiride Metolazone Infliximab Cetirizine Isoniazid Halothane Methyldopa Macrolide antibiotics Tricyclic antidepressants Amoxicillin-clavulanate Azathioprine Oxypenicillins NSAID's Chlorpromazine Troglitazone Celecoxib Carbamazepine Repaglinide Terbinafine Cephalexin Fenofibrate Hydrochlorothiazides Ticlopidine Pyritinol Methimazole Metformin Gemcitabine Orlistat Celecoxib Gabapentin Propafenone Acitretin Isoflurane Bupropion Captopril Resperidone Propafenone Chlorambucil Risperidone Glimepiride Proplthiouracil Itraconazole Dextromethorphan Atorvastatin Senna Cascara sagrada Lycopodium serratum Carmustine Toxins: paraquat, methylenedianiline Flucoxacillin Dextropropxyphene Tenoxicam Gold Therapy Pioglitazone Amoxicillin-clavulanate Aceprometazine Ajmaline Amineptine Amitriptyline Amoxicillin/clavulanic acid Ampicillin Azathioprine Barbiturates Carbamazepine Carbutamide Chlorothiazide Chlorpromazine Cimetidine Ciprofloxicin Clindamycin Co-trimoxazole Cromolyn sodium Cyamemazine Cyclohexyl propionate Cyproheptadine D-penicillamine Diazepam Erythromycin Estradiol Flucloxacillin Glibenclamide Glycyrrhizin Haloperidol Ibuprofen Imipramine Methyltestosterone Norandrostenolone Phenylbutazone Phenytoin Prochlorperazine Terbinafine Tetracyclines Thiabendazole Tiopronin Trifluoperazine Tolbutamide Trimethoprim-sulfamethoxazole Troleandomycin Xenalamine Floxuridine Intralesional agents:Hypertonic saline, iodine solution, formaldehyde, absolute alcohol, silver nitrate.