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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Epidemiology. 2011 May;22(3):313–319. doi: 10.1097/EDE.0b013e3182125f9c

TABLE 2.

Comparison of twins and singletons according to oral cleft phenotype, sex and zygosity; Denmark 1968-2004.

Cohort Phenotype/Source Total No. % Male Twins vs. Singletons Prevalence Ratio
(95% CI)a
All Oral Cleft Twins
Total Oral Cleft 136 64 1.15 (0.95-1.38)
 Cleft lip 40 73 1.09 (0.77-1.53)
 Cleft lip and palate 63 76 1.43 (1.09-1.9)
 Cleft palate 33 30 0.87 (0.61-1.26)
Monozygotic Twins
Total Oral Cleft 22 59 1.29 (0.77-2.17)
 Cleft lip 9 56 1.71 (0.83-3.52)
 Cleft lip and palate 9 78 1.42 (0.65-3.12)
 Cleft palate 4 25 0.74 (0.22-2.45)
Dizygotic Twins
Total Oral Cleft 76 61 1.14 (0.90-1.45)
 Cleft lip 17 65 0.82 (0.50-1.37)
 Cleft lip and palate 39 77 1.57 (1.13-2.20)
 Cleft palate 20 25 0.94 (0.59-1.49)
a

Controlled for cluster