TABLE 2.
Cohort | Phenotype/Source | Total No. | % Male | Twins vs. Singletons Prevalence Ratio (95% CI)a |
---|---|---|---|---|
All Oral Cleft Twins | ||||
Total Oral Cleft | 136 | 64 | 1.15 (0.95-1.38) | |
Cleft lip | 40 | 73 | 1.09 (0.77-1.53) | |
Cleft lip and palate | 63 | 76 | 1.43 (1.09-1.9) | |
Cleft palate | 33 | 30 | 0.87 (0.61-1.26) | |
Monozygotic Twins | ||||
Total Oral Cleft | 22 | 59 | 1.29 (0.77-2.17) | |
Cleft lip | 9 | 56 | 1.71 (0.83-3.52) | |
Cleft lip and palate | 9 | 78 | 1.42 (0.65-3.12) | |
Cleft palate | 4 | 25 | 0.74 (0.22-2.45) | |
Dizygotic Twins | ||||
Total Oral Cleft | 76 | 61 | 1.14 (0.90-1.45) | |
Cleft lip | 17 | 65 | 0.82 (0.50-1.37) | |
Cleft lip and palate | 39 | 77 | 1.57 (1.13-2.20) | |
Cleft palate | 20 | 25 | 0.94 (0.59-1.49) |
Controlled for cluster